Endocrine Abstracts

Introduction: Pheochromocytoma is a rare neuroendocrine tumor. It is usually diagnosed in subjects between 40 and 50 years of age. The occurrence of pheochromocytoma in the elderly is much rarer and has its own particularities. We report the case of a 70-year-old female patient with invasive pheochromocytoma.Case presentation: A 70-year-old female patient with a history type 2 diabetes for 18 years on oral antidiabetics and insulin. The history of his di...

Introduction: Primary hyperparathyroidism is the most common endocrinopathy after diabetes and thyroid diseases. Most often, the diagnosis is made at the asymptomatic stage due to the frequent phosphocalcic assessment objectifying hypercalcemia. Much more rarely, primary hyperparathyroidism is diagnosed at the stage of digestive, renal or bone complications. We report the case of a young patient with a femoral fracture that revealed primary hyperparathyroidism.<p class="ab...

Introduction: Centropontic myelinolysis (CPM) is a neurological pathology related to axonal demyelination lesions, often localized at the pontine level. For a long time, this condition was attributed to rapid correction of hyponatremia. A few cases of PCM with normal natraemia have been described, in a context of undernutrition, chronic alcoholism, hypokalaemia or hyperglycaemia.Patient and observation: We report the case of an 18 years old patient, type...

Introduction: Noonan syndrome (NS) is an autosomal dominant genetic disorder characterized by the combination of facial dysmorphia, short stature and congenital heart disease. The mutation of the PTPN11 gene is present in 50% of cases, recently the mutation of other genes was found, notably KRAS and SOS1. We report the case of a patient followed in our department for NS with a SOS1 gene mutation.Case report: A 4 years old male patient, referred to our de...

Introduction: Primary biliary cholangitis (PBC) is a rare chronic cholestatic liver disease, which is most likely of autoimmune origin. It is often associated with other autoimmune diseases, although it is rarely seen with Basedow.Observation: We report the case of a 38 years old patient, chronic smoker, who presents clinical and biological hyperthyroidism related to Basedow, treated with synthetic antithyroid drugs for years with poor compliance and not...